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. 2017 Apr;361(1):181–189. doi: 10.1124/jpet.116.239376

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Fig. 4. — Self-administration dose-response curves for MDPV (squares), cocaine (circles), and methamphetamine (diamonds) obtained under a PR schedule of reinforcement (upper-left panel). Self-administration dose-response curves of MDPV (upper-right panel), cocaine (lower-left panel), and methamphetamine (lower-right panel) in high responders (n = 7, solid symbols) and low responders (n = 9, open symbols). Abscissa: SAL represents data obtained when saline was available for infusion, whereas doses refer to the unit dose of each drug available for infusion expressed as mg/kg/infusion on a log scale. Left ordinate: total infusions obtained during the session. Right ordinate: final ratio completed during the session. Error bars represent ±S.E.M. Pound signs indicate statistical significance compared with low responders: #P < 0.05.