Fig. 5. (A) ThT fibrillation kinetics of 10 μM IAPP in the absence (grey curve) or presence of 50 μM test compounds. Each curve represents the average of six replicates. (B) Times to half-maximal fibrillation (t _1/2). Conditions: 500 μg mL^–1 DOPG/DOPC liposomes (1 : 1), 20 mM potassium phosphate buffer, 100 mM sodium chloride, pH 7.2, 25 °C.† .