Effect of 3-HT on DNA damage and cell cycle regulatory proteins in A2780/CP70 and OVCAR-3 cells. (A) The DNA damage regulatory proteins in A2780/CP70 and OVCAR-3 cells were detected by western blotting, cells were incubated with 3-HT at 0–8 µM for 24 h, cell lysates were prepared and then subjected to western blotting, GAPDH was used as internal control. (B and C) A2780/CP70 and OVCAR-3 protein expression data were expressed as means ± SEM of three independent experiments. *P<0.05, **P<0.01, ***P<0.001. (D) The cell cycle regulatory proteins in A2780/CP70 and OVCAR-3 cells were detected by western blotting, cells were incubated with 3-HT at 0–8 µM for 24 h, cell lysates were prepared and then subjected to western blotting, GAPDH was used as internal control. (E and F) A2780/CP70 and OVCAR-3 protein expression data were expressed as means ± SEM of three independent experiments. *P<0.05, **P<0.01, ***P<0.001.