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. 2017 Jan 6;21:16-080. doi: 10.7812/TPP/16-080

Table 2.

Demographics of all pregnant women with and without a history of penicillin allergy who delivered between 2009 and 2014

Demographic characteristic History of penicillin allergy No history of penicillin allergy p value
Age, years, mean (SD) 30.34 (5.78) 29.55 (5.83) < 0.0001
Total deliveriesa 16,084 185,232
Number of unique women 14,233 163,500
Active drug-class allergies before delivery, mean (SD) 1.48 (0.85) 0.63 (0.57) < 0.0001
Number of live births 16,387 188,498
Cesarean deliveries, no. (%) 5198 (32.32) 56,079 (30.28) < 0.0001
Total days in hospital from the date of initial admission for delivery to 6 months after delivery for women, mean (SD) 3.55 (1.79) 3.45 (2.04) < 0.0001
Total days in hospital from the date of initial admission for delivery to 6 months after delivery for women with spontaneous vaginal delivery, mean (SD) 3.17 (1.45)b 3.11 (1.50)c < 0.0001
Total days in hospital from the date delivery to 6 months after delivery for the infants, mean (CI) 4.48 (4.33–4.62) 4.29 (4.25–4.33)
Antibiotic exposure ± 3 days from delivery, no. (%) 9126 (56.74) 102,317 (55.24) 0.0002
Total antibiotic courses 18,755 242,000 < 0.0001d
Total new antibiotic allergies within 30 days of peripartum antibiotic exposures, mean (CI) 0.0106 (0.0089–0.0124) 0.0011 (0.0009–0.0013)
New Clostridium difficile infections within 90 days of delivery, no. (%) 7 (0.04) 85 (0.05) 0.8928
a

A woman may have multiple deliveries during the study interval, and each delivery is counted as an independent event. All descriptive statistics and statistical tests are at delivery level, not patient level.

b

n = 10,886 women.

c

n = 129,153 women.

d

p value for testing whether the mean number of courses of antibiotic is different for those with penicillin allergy from those without penicillin allergy (among those exposed).

CI = confidence interval; SD = standard deviation.