Table 2. Mean and standard deviation (SD), Pearson correlation coefficients, root mean square (RMS) errors and coefficients of variation (%CV) of the measurements in subchondral bone compartments imaged at 5 and 10 μm/pixel resolution.

Microstructural parameter		Mean ± SD		Pearson r	RMS error	CV (%)
		5 μm/pixel	10 μm/pixel			5 μm/pixel	10 μm/pixel
Subchondral bone plate volume (mm3)	Medial	0.0606±0.0170	0.0825±0.0259	0.85**	0.0096	28.1	33.5
	Lateral	0.0352±0.0051	0.0412±0.0051	0.81**	0.0032	14.6	16.2
Subchondral bone plate thickness (μm)	Medial	161.6±46.1	210.7±68.9	0.84**	26.3	28.5	32.0
	Lateral	91.3±13.9	100.5±13.7	0.81**	8.6	15.2	17.4
Trabecular total volume (mm3)	Medial	0.0688±0.0172	0.0485±0.0258	0.84**	0.0099	25.1	53.3
	Lateral	0.0952±0.0052	0.0898±0.0051	0.81**	0.0032	5.5	5.7
Trabecular bone volume (mm3)	Medial	0.0505±0.0060	0.0394±0.0167	0.40	0.0058	11.9	42.5
	Lateral	0.0505±0.0027	0.0585±0.0039	-0.19	0.0028	5.3	6.7
Trabecular BV/TV (%)	Medial	76.2±12.9	85.1±9.2	0.94****	4.8	17.0	9.6
	Lateral	53.3±4.5	65.3±5.0	0.05	4.8	8.5	11.6

Subchondral bone plate volume, thickness, and trabecular total volume, bone volume, and BV/TV of the medial and lateral aspects of the tibial plateau quantified in 5 and 10 μm/pixel scans were paired and analysed. The mean and standard deviation (SD) of each parameter is reported as well as the Pearson’s correlation coefficient (r) obtained from parametric analysis (**P<0.01 and ****P<0.0001). The RMS error obtained from linear regression analysis and the %CV for both resolutions are also reported (n = 10 in which medial/lateral aspects of the plateau in right and left legs were pooled together).