Fig 2. Perfusion measured at endpoint is not significantly different between hind limbs, regardless of treatment.

(A) Schematic representation of treatment groups. “Sham” group mice received sham injections in both hind limbs. “VEGF” mice received sham injection in the right hind-limb, VEGF in the contralateral limb. “VEGF+ANG1” mice received VEGF in the right hind-limb and VEGF+ANG1 in the contralateral limb. “ANG1” mice received ANG1 in the left hind limb and a sham injection in the contralateral limb. (B) Blood flow (left) and blood volume (right) did not differ between hind limbs, allowing for perfusion measurements to be assessed based on the averaged BF and BV following treatment. n = 6, P < 0.05, by Wilcoxan signed-rank test.