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. 2017 Mar 17;12:2129–2142. doi: 10.2147/IJN.S126016

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Physical characterization of the TPNPs.

Notes: (A) Size of the PTX-loaded PLGA nanoparticles and TPNPs. (B) TEM images (n.3) of (I) a PLGA core, (II) a hCTL membrane vesicle, (III) a TPNP, and (IV) multiple TPNPs. All scale bars =100 nm. (C) Cumulative in vitro release of PTX from TPNPs (n=3).

Abbreviations: TPNPs, T-lymphocyte membrane-coated PLGA nanoparticles; PTX, paclitaxel; PLGA, poly-lactic-co-glycolic acid; PLGA–PTX, PTX-loaded PLGA nanoparticles; T-PLGA–PTX, PTX-loaded PLGA nanoparticles with hCTL membrane encapsulation; TEM, transmission electron microscopy.