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. 2017 Mar 17;12:2129–2142. doi: 10.2147/IJN.S126016

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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In vivo targeting and biodistribution of TPNPs.

Notes: (A) Fluorescence micrographs of resected tumors. Green, DiO; red, CD31; blue, DAPI. Scale bars =1,000 μm. (B) In vivo images of real-time tumor targeting characteristics of the TPNPs, with or without LDI. (C) Ex vivo images of tumors and organs of the sacrificed mice at 96 h after the injection. (D) Biodistribution of the nanoparticles at 96 h after injection (n=3). NS, no significant difference; *P<0.05.

Abbreviations: LDI, low-dose irradiation; PLGA, poly-lactic-co-glycolic acid; TPNPs, T-lymphocyte membrane-coated PLGA nanoparticles.