Table 2.
Change of signs and symptoms according to the category of dry eye diagnosis
| Category of dry eye diagnosis before surgery | Examination point
|
Comparison within-group, P-value | |
|---|---|---|---|
| Before surgery | 4 weeks after surgery | ||
| Tear breakup time (seconds) | |||
| Total | 0.036a,* | ||
| Mean ± SD | 4.75±2.63 | 4.50±2.67 | |
| Number of patients | 433 | 433 | |
| Non-dry eye | <0.001a,** | ||
| Mean ± SD | 7.02±2.62 | 5.74±2.95 | |
| Number of patients | 131 | 131 | |
| Probable | 0.269a | ||
| Mean ± SD | 3.96±2.10 | 4.14±2.41 | |
| Number of patients | 217 | 217 | |
| Definite | 0.169a | ||
| Mean ± SD | 3.24±1.32 | 3.53±2.13 | |
| Number of patients | 85 | 85 | |
| Probable + definite | 0.105a | ||
| Mean ± SD | 3.76±1.94 | 3.96±2.35 | |
| Number of patients | 302 | 302 | |
| Corneal and conjunctival fluorescein staining scores | |||
| Total | 0.012a,* | ||
| Mean ± SD | 1.5±1.4 | 1.6±1.3 | |
| Number of patients | 433 | 433 | |
| Non-dry eye | <0.001a,** | ||
| Mean ± SD | 0.7±0.8 | 1.2±1.2 | |
| Number of patients | 131 | 131 | |
| Probable | <0.001a,** | ||
| Mean ± SD | 1.1±1.0 | 1.5±1.2 | |
| Number of patients | 217 | 217 | |
| Definite | <0.001a,** | ||
| Mean ± SD | 3.5±1.0 | 2.6±1.2 | |
| Number of patients | 85 | 85 | |
| Probable + definite | 0.720a | ||
| Mean ± SD | 1.8±1.5 | 1.8±1.3 | |
| Number of patients | 302 | 302 | |
| Schirmer I test | |||
| Total | 0.209a | ||
| Mean ± SD | 11.8±9.0 | 12.3±9.9 | |
| Number of patients | 433 | 433 | |
| Non-dry eye | 0.205a | ||
| Mean ± SD | 14.7±9.4 | 15.7±10.5 | |
| Number of patients | 131 | 131 | |
| Probable | 0.252a | ||
| Mean ± SD | 10.5±8.9 | 11.2±9.3 | |
| Number of patients | 217 | 217 | |
| Definite | 0.388a | ||
| Mean ± SD | 10.4±7.6 | 9.8±8.8 | |
| Number of patients | 85 | 85 | |
| Probable + definite | 0.534a | ||
| Mean ± SD | 10.5±8.5 | 10.8±9.2 | |
| Number of patients | 302 | 302 | |
| Total score of 12 subjective symptoms | |||
| Total | <0.001b,** | ||
| Mean ± SD | 8.8±5.5 | 4.5±4.6 | |
| Number of patients | 431 | 431 | |
| Non-dry eye | <0.001b,** | ||
| Mean ± SD | 6.8±5.4 | 3.6±4.2 | |
| Number of patients | 131 | 130 | |
| Probable | <0.001b,** | ||
| Mean ± SD | 9.2±5.1 | 4.5±4.4 | |
| Number of patients | 216 | 216 | |
| Definite | <0.001b,** | ||
| Mean ± SD | 11.1±5.6 | 5.8±5.2 | |
| Number of patients | 84 | 85 | |
| Probable + definite | <0.001b,** | ||
| Mean ± SD | 9.7±5.3 | 4.9±4.7 | |
| Number of patients | 300 | 301 | |
Notes:
a
One-sample t-test.
b
One-sample Wilcoxon rank-sum test, corneal and conjunctival fluorescein staining scores were evaluated in three areas (the temporal bulbar conjunctiva, nasal bulbar conjunctiva, and cornea), scored on a 0- to 3-point scale (0: no damage to 3: damage in the entire area) and then totaled (maximum =9 points). Subjective symptom score; score 0= never, score 1= rarely, score 2= sometimes, score 3= all of the time.
*
P<0.05;
**
P<0.001.
Abbreviation: SD, standard deviation.