Table 6.
Change of tear breakup time (seconds) in prospective randomized study
| Examination point
|
Amount of change | Comparison within-group one-sample t-test (P-value) | ||
|---|---|---|---|---|
| Before treatment (4 weeks after surgery) | After treatment (8 weeks after surgery) | |||
| Total patients | ||||
| DQS | ||||
| Mean ± SD | 3.32±1.62 | 3.92±1.87 | 0.60±2.11 | 0.015* |
| Median | 3.33 | 3.67 | 0.67 | |
| Number of patients | 75 | 75 | 75 | |
| AT | ||||
| Mean ± SD | 3.13±1.69 | 3.48±1.69 | 0.35±1.76 | 0.085 |
| Median | 3.00 | 3.33 | 0.33 | |
| Number of patients | 79 | 79 | 79 | |
| Comparison between groups two-sample t-test (P-value) | 0.489 | 0.125 | 0.410 | |
| The definite dry eye patient before surgery | ||||
| DQS | ||||
| Mean ± SD | 3.25±1.27 | 4.18±1.82 | 0.93±1.61 | 0.018* |
| Median | 3.33 | 4.17 | 1.00 | |
| Number of patients | 20 | 20 | 20 | |
| AT | ||||
| Mean ± SD | 3.00±1.94 | 2.99±1.71 | −0.01±1.88 | 0.972 |
| Median | 2.67 | 3.00 | 0.00 | |
| Number of patients | 25 | 25 | 25 | |
| Comparison between groups two-sample t-test (P-value) | 0.622 | 0.028* | 0.081 | |
Note:
*
P<0.05.
Abbreviations: AT, artificial tears; DQS, diquafosol ophthalmic solution; SD, standard deviation.