Table 1. Clinico-pathologic characteristics.
| Characteristics | LEEP combined with cold coagulation (n=144) | LEEP alone (n=354) | P-value |
|---|---|---|---|
| Age (yr) | 0.17 | ||
| <40 | 57 (39.6) | 165 (46.6) | |
| ≥40 | 87 (60.4) | 189 (53.4) | |
| Indication of LEEP | <0.01 | ||
| Abnormal cytology or high-risk HPV infection | 51 (35.4) | 85 (24) | |
| CIN 1 on punch biopsy | 23 (16) | 8 (2.3) | |
| CIN 2 on punch biopsy | 21 (14.6) | 89 (25.1) | |
| CIN 3 on punch biopsy | 49 (34) | 172 (48.6) | |
| Final histology | <0.01 | ||
| Chronic cervicitis | 42 (29.2) | 3 (0.8) | |
| CIN 1 | 19 (13.2) | 40 (11.3) | |
| CIN 2 | 24 (16.6) | 70 (19.8) | |
| CIN 3 | 59 (41) | 241 (68.1) | |
| Exocervical margin | 0.26 | ||
| Positive | 11 (7.6) | 40 (11.3) | |
| Negative | 133 (92.4) | 314 (88.7) | |
| Endocervical margin | 0.45 | ||
| Positive | 24 (17.9) | 70 (19.8) | |
| Negative | 120 (82.1) | 284 (80.2) | |
| Deep cervical margin | 1.00 | ||
| Positive | 2 (1.4) | 6 (1.7) | |
| Negative | 142 (98.6) | 348 (98.3) |
Values are presented as number (%).
LEEP, loop electrosurgical excision procedure; HPV, human papillomavirus; CIN, cervical intraepithelial neoplasia.