Table 3. Cox's proportional hazard analysis for factors affecting high-risk human papillomavirus infection after loop electrosurgical excision procedure.

Characteristics	Univariate			Multivariate
	HR	95% CI	P-value	Adjusted HR	95% CI	P-value
All patients
Age ≥40 yr	1.36	0.94–1.98	0.10	1.39	0.95–2.03	0.09
CIN 3	1.51	1.06–2.16	0.02	2.07	1.38–3.08	<0.01
Positive exocervical margin	1.10	0.61–1.99	0.76	0.98	0.53–1.80	0.95
Positive endocervical margin	1.45	0.95–2.21	0.09	1.71	1.10–2.68	0.18
Positive deep cervical margin	3.36	1.37–8.24	<0.01	4.11	1.63–10.39	<0.01
Cold coagulation	0.82	0.56–0.79	0.01	0.64	0.43–0.96	0.03
Patients with CIN 2 or CIN 3
Age ≥40 yr	1.32	0.97–1.99	0.19	1.36	0.89–2.08	0.16
CIN 3	1.89	1.24–2.89	<0.01	2.25	1.45–3.51	<0.01
Positive exocervical margin	0.87	0.49–1.57	0.65	0.96	0.53–1.75	0.89
Positive endocervical margin	1.25	0.79–1.96	0.34	1.39	0.84–2.22	0.17
Positive deep cervical margin	2.02	0.98–4.63	0.06	2.78	1.15–6.71	0.02
Cold coagulation	0.75	0.46–0.92	<0.01	0.59	0.56–0.99	0.04

HR, hazard ratio; CI, confidence interval; CIN, cervical intraepithelial neoplasia.