Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 24;8:346. doi: 10.3389/fimmu.2017.00346

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 van den Bosch, Caliskan, Kraaij, Constantinescu, Manintveld, Leenen, von der Thüsen, Clahsen-van Groningen, Baan and Rowshani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

CD16+ cells in graft tissue are monocytes and accumulate upon rejection. The expression of CD14 and CD16 was analyzed in biopsies at two time points; non-rejection (NR; n = 25) and rejection (R; n = 25) and compared intra-individually. The absolute number of cells is depicted for (A) CD14+CD16−, (B) CD14+CD16+, and (C) CD14−CD16+. The expression of (D) CD56 was measured using immunohistochemistry, analyzed by ImageJ and depicted as mean % positive stained area. The absolute numbers of cells of (E,F) CD56+CD16− and CD56+16+ were determined. A representative overview of rejecting endomyocardial tissue stained for (G) CD56 (green) and CD16 (red) at 20× magnification is shown. A representative overview of rejecting endomyocardial tissue stained for (H) CD14 (green), (I) CD16 (green) and CD68 (red) at 20× magnification is given (*p < 0.05, ***p < 0.001).