Table 2.

Results summary for NRT and cancer

CAF no.a	References	Exposure	Endpoint	Casesb	Hazard ratioc (95 % CI)	Adjustments
1	Murray et al. (2009)	Mean daily NRT use	Lung cancer	75	1.02 (0.95–1.09)	d
					1.04 (0.97–1.12)	e
			GI cancer	33	0.97 (0.86–1.10)	d
					0.97 (0.82–1.14)	e
			All cancer	203	1.00 (0.96–1.05)	d
					1.01 (0.97–1.06)	e

^a CAF critical assessment form. CAF 1 is a prospective study

^bDuring the 7.5-year follow-up period following the 5-year period of the Lung Health Study

^cPer piece of gum used per day on average during the Lung Health Study

^dBaseline age, sex, cigarettes per day and lifetime pack-years of smoking

^eAlso adjusted for pack-years cigarette use over the 5-year period of the Lung Health Study