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. 2017 Mar 11;79(4):651–660. doi: 10.1007/s00280-016-3237-x

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Anti-tumor activity of pembrolizumab per RECIST v1.1 by central review. a Best change from baseline in the sum of the longest target lesion diameters for each patient. b Treatment exposure and duration of response per patient. c Longitudinal changes in the sum of the longest target lesion diameters for each patient