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. 2016 Oct 20;91(4):1595–1612. doi: 10.1007/s00204-016-1876-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — a Monoclonal antibody structure with binding site for antigen, FcγR and FcRn receptor as well as glycosylation sites (Glycan); Ag antigen, CDC complement-dependent cytotoxicity, ADCC antibody-dependent cell cytotoxicity, ADCP antibody-dependent cell phagocytosis, b glycosylation profile at N297 residue of the Fc region of antibodies. The bold line indicates core structures, and dotted line indicates variable structures. Gal galactose, SA sialic acid, man mannose, GlcNAc N-acetylglucosamine, Fuc fucose, Asn asparagine (N297)