TABLE 1.

Effects of minocycline and 1-methyl-dl-tryptophan treatments on plasma levels of the inflammatory cytokines IFN-γ and IL-1β in mice infected with T. gondii at 10 days postinfection^a

Treatment	Mean level of protein (pg/ml) ± SD
	IL-1β	IFN-γ
PBS-PBS	ND	ND
PBS-Mino	47.2 ± 4.6 a	82.5 ± 28.4 a
T. gondii-PBS	645.6 ± 34.6 b	410.89 ± 87.7 b
T. gondii-Mino	24.1 ± 4.4 a	136.6 ± 7.6 c
PBS-vehicle	ND	ND
PBS–1-MT	ND	26.5 ± 5.3 a
T. gondii-vehicle	676.0 ± 32.5	459.6 ± 43.2 b
T. gondii–1-MT	619.5 ± 26.7	433.3 ± 40.0 b

^aData represent average mean values ± standard deviations {n = 5 or 6; one mouse each died due to infection in the T. gondii-PBS group [for IL-1β, F_{(3, 22)} = 231.7 and P = 0.0001; for IFN-γ, F_{(3, 22)} = 329.4 and P = 0.0001] and the T. gondii-vehicle group [for IL-1β, F_{(3, 22)} = 156.7 and P = 0.0001; for IFN-γ, F_{(3, 22)} = 326.0 and P = 0.0001]}. Different letters indicate statistically significant differences among the groups by one-way ANOVA plus Tukey-Kramer post hoc analysis. ND, not detected.