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. 2017 Feb 4;389(10068):505–518. doi: 10.1016/S0140-6736(16)32621-6

Table 5.

Frequency of solicited adverse events by time since vaccination in children and adults.

0–30 min 31 min to 3 days 4–14 days
Children aged between 6–<18 years (n=194)
Arthralgia 0 3 (3·5%) 1 (9.1%)
Diarrhoea 0 0 1 (9·1%)
Fatigue 0 10 (11·6%) 1 (9·1%)
Fever 0 1 (1·2%) 1 (9·1%)
Headache 0 47 (54·7%) 4 (36·4%)
Induration 0 0 0
Injection pain 0 9 (10·5%) 0
Muscle pain 0 4 (4·7%) 1 (9·1%)
Myalgia 0 4 (4·7%) 1 (9·1%)
Vomiting 0 1 (1·2%) 0
Other adverse events 0 7 (8·1%) 1 (9·1%)
Total 0 86 (100·0%) 11 (100·0%)
Adults aged 18 years and older (n=5643)
Arthralgia 3 (2%) 851 (13·5%) 79 (12·3%)
Diarrhoea 0 53 (0·8%) 15 (2·3%)
Fatigue 5 (3·3%) 1233 (19·5%) 112 (17·4%)
Fever 2 (1·3%) 8 (0·1%) 2 (0·3%)
Headache 41 (27·3%) 1563 (24·7%) 177 (27·5%)
Induration 0 1 (<1%) 0
Injection pain 70 (46·7%) 362 (5·7%) 8 (1·2%)
Muscle pain 7 (4·7%) 875 (13·8%) 55 (8·5%)
Myalgia 6 (4·0%) 816 (12·9%) 47 (7·3%)
Vomiting 0 21 (0·3%) 4 (0·6%)
Other adverse events 16 (10·7%) 537 (8·5%) 145 (22·5%)
Total 150 (100·0%) 6320 (100·0%) 644 (100·0%)

Data are n (%); individuals might have had more than one adverse event.