Table 1. Substrates of different origin metabolized by Faecalibacterium prausnitzii isolates in vitro (batch pure cultures) as reported by (Duncan, et al. 2002; Lopez-Siles, et al. 2012).
| Substrate | No. of utilizers | No. of strains tested |
|---|---|---|
| Simple carbohydratesa | ||
| Glucose | 11 | 11 |
| Fructose | 4 | 4 |
| Cellobiose | 10 | 11 |
| Maltose | 10 | 11 |
| Galactose | 9 | 10 |
| Galacturonic acid | 7 | 9 |
| Sucrose | 2 | 4 |
| Melezitose | 1 | 4 |
| Trehalose | 1 | 4 |
| Rhamnose | 1 | 11 |
| Amino acidsb | ||
| Arginine | 4 | 4 |
| Histidine arylamide | 4 | 4 |
| Glycine arylamide | 2 | 4 |
| Diet-derivedc | ||
| Fructo-oligosacharides | 4 | 4 |
| Pectin (apple) | 10 | 10 |
| Inulin (chicory) | 9 | 11 |
| Host-derivedd | ||
| Glucosamine HCl | 10 | 10 |
| N-acetylglucosamine | 9 | 10 |
| Glucuronic acid | 6 | 10 |
Other simple carbohydrates tested but non-metabolized are mannitol (0/3), melibiose (0/4), raffinose (0/4), ribose (0/4), fucose (0/10), arabinose (0/11) and xylose(0/11).
Other amino acids tested but non-metabolized are alanine (0/4), glutamic acid (0/4), glutamyl (0/4), leucine (0/4), leucine-glycine (0/4), phenylalanine (0/4), proline (0/4), pyroglutamic acid (0/4), serine (0/4), tyrosine (0/4).
Other diet-derived carbohydrates not metabolized are arabinogalactan (0/10), citrus pectin (0/10), polygalacturonic acid (0/10), xylan (0/10) and potato starch (8/11) which depends on the solubility of the starch as F. prausnitzii does not metabolize starch.
Other host-derived carbohydrates not metabolized are chondroitin sulfate (0/10), heparin (0/10), hyaluronic acid (0/10), pig gastric mucin (0/10).