Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of bupivacaine and procaine on cellular ROS (reactive oxygen species) production detected by dihydroethidium (DHE) staining and dichlorofluorescein diacetate (DCFH-DA) in SH-SY5Y cells (A,E) and DRG neurons (B,F). Quantitative analysis of the fluorescence intensity per cell showed that bupivacaine treatment was followed by a rapid burst of ROS, while procaine increased the peroxidation content. *P < 0.05, **P < 0.01, ***P < 0.001.
