Figure 2. Impaired hepatic lipid synthesis and TG secretion in the absence of Zbtb20.

Male control or LZB20KO mice at the age of 3–4 months were fed on normal chow. (a) Plasma TG levels after intraperitoneal injection of tyloxapol following a 4-h fast. n=4. (b) In vivo hepatic lipogenesis was determined by measuring the incorporation of ³H-H₂O into fatty acids and sterols of the liver. n=7 per group. Data are represented as mean±s.e.m. *P<0.05; **P<0.01 versus control (Student's t-test).