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. 2017 Mar 24;7:45034. doi: 10.1038/srep45034

Figure 6. Effects of length of freezing and donor drug use on SE-mediated HIV-1 inhibition.

Figure 6

(a,b) Infectivity of HIV-1 and cell viability in a pre-incubation infection model where SE (100 μg/ml) or vehicle PBS was pre-incubated with 8 RT units of HIV-1 NL4.3 for 1 hour at 37 °C before infection of TZM-bl indicator cells for 24 h. (a) Infectivity and (b) Cell viability. (c,d) Infectivity of HIV-1 and cell viability in a pre-treatment infection model where SE (100 μg/ml) or vehicle PBS was added to TZM-bl indicator cells for 24 h before infecting cells with 8 RT units of HIV-1 NL4.3 for 24 h. (c) Infectivity and (d) Cell viability. Vehicle is set as reference at 100% for infectivity and viability. Statistics was performed by comparing infectivity or viability values from each donor to vehicle control. Significance was determined by student’s t test. Differences with p values of 0.05 or less are considered significant *p < 0.05, **p < 0.001. Error bars are SD. ns = not significant.