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. 2017 Mar 24;7:44689. doi: 10.1038/srep44689

Figure 6. Resveratrol reduces ICAM-1 expression in the thoracic aorta ECs of TNF-α-treated WT mice but not miR-221/-222 KO mice.

Figure 6

(A) Immunohistochemical staining for CD31 (an EC marker) and ICAM-1 expression in serial sections from the thoracic aortas of WT and miR-221/-222 KO mice. Mice were treated with DMSO, TNF-α, resveratrol + TNF-α, or resveratrol alone. The lumen is the uppermost portion in all sections. The reaction product is indicated by arrowheads. Bar = 40 μm. (B) Western blot analysis of ICAM-1 expression in aortic tissues of C57BL6J and miRNA-221/222 KO mice. Blots are cropped for clarity; full blots are shown in the Supplementary file.