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. 2017 Mar 24;7:43107. doi: 10.1038/srep43107

Figure 4. Effects of LOS on p-Rac1 expression and ROS activity in the PVN of salt-induced hypertensive rats.

Figure 4

ROS activity was measured by fluorescent-labeled dihydroethidium (DHE) staing. High salt (HS) intake rats had higher level of p-Rac1 expression and immunofluorescent intensity of DHE when compared with control rats. Bilateral PVN infusion of LOS for14 days reduced the levels of superoxide and p-Rac1 expression in the PVN of HS rats. (A) Immunohistochemistry for p-Rac1 and the immunofluorescence for superoxide in the PVN in different groups. (B) Column diagram showing the effects of LOS on the p-Rac1 positive neurons in the PVN in different groups. (C) Column diagram showing immunofluorescent intensity of DHE in the PVN in different groups. Values are expressed as means ± SE. *P < 0.05 vs NS groups (NS + PVN LOS or NS + aCSF); P < 0.05 HS + LOS vs HS + aCSF.