Figure 1.
Relative mRNA expression levels of IL1β (a), CXCL8 (d), IL6 (g) and IL17 (j) in healthy, interdigital dermatitis (ID) and footrot biopsies from the ovine interdigital skin. Association between virulent Dichelobacter nodosus load and relative mRNA expression of IL1β (b), CXCL8 (e), IL6 (h) and IL17 (k) in healthy samples with low and high expression levels of these cytokines (blue symbols). Association between virulent D. nodosus load and relative mRNA expression of IL1β (c), CXCL8 (f), IL6 (i) and IL17 (l) in footrot samples with low and high expression levels of these cytokines (red symbols). Median is represented by black bars. Kruskal-Wallis test (Mann Whitney test, non-parametric) was performed to verify the association between virulent D. nodosus load and expression of IL1β, IL6, CXCL8 and IL17. Kruskal-Wallis test (Dunn’s multiple comparison test, non-parametric) was used to verify the association between cytokines relative mRNA expression levels with clinical conditions, *p < 0.037.