Fig. 1.

Echocardiography of the three patients. a Patient 1. Severe biventricular non-obstructive hypertrophic cardiomyopathy (interventricular septal thickness 12 mm, +5.2 Z-score) and virtual cavity in the left ventricle. b Patient 2. Hypertrophic cardiomyopathy predominant left (interventricular septal thickness 8 mm, +3.2 Z-score). c Patient 3. Severe hypertrophic cardiomyopathy (interventricular septal thickness 7 mm, +2.8 Z-score), with virtual cavity in the left ventricle and cardiac function alteration