Table 3.
Health care costs and resource use in the 1-year pre-index period
| Overall population | Matched population | |||||
|---|---|---|---|---|---|---|
| EIAED (n = 2752) |
nEAAED (n = 2137) |
p valuea | EIAED (n = 951) |
nEAAED (n = 951) |
p valuea | |
| All-cause direct health care costs in the 1-year pre-index period, £ | ||||||
| Mean (SD) | 5618 (7387) | 4613 (6007) | <0.0001 | 4540 (6765) | 4416 (5944) | 0.6724 |
| Median (P10–P90) | 3014 (495–14,070) | 2516 (568–11,657) | 2333 (452–10,863) | 2283 (448–11,180) | ||
| Epilepsy-related direct health care costs in the 1-year pre-index period, £ | ||||||
| Mean (SD) | 997 (2361) | 633 (1965) | <0.0001 | 804 (2134) | 726 (2201) | 0.4314 |
| Median (P10–P90) | 42 (0–2797) | 11 (0–2188) | 23 (0–2599) | 11 (0–2599) | ||
| Health care resource use per patient in the 1-year pre-index period Mean (SD) number of: | ||||||
| GP practice consultations | 35.13 (29.55) | 43.69 (36.33) | <0.0001 | 36.48 (31.92) | 37.04 (31.15) | 0.6973 |
| A&E visits | 0.83 (1.26) | 0.70 (1.28) | 0.0003 | 0.72 (1.41) | 0.70 (1.15) | 0.6173 |
| Outpatient non-A&E referrals | 0.96 (1.45) | 1.27 (1.40) | <0.0001 | 1.08 (1.35) | 1.08 (1.29) | 0.9446 |
| Inpatient hospitalizations | 1.64 (5.63) | 1.20 (2.70) | 0.0004 | 1.44 (7.27) | 1.22 (3.41) | 0.4126 |
| Hospitalization duration, mean (SD), days | ||||||
| 6.96 (19.70) | 3.64(11.89) | <0.0001 | 4.30 (11.32) | 4.09 (11.48) | 0.6873 | |
Abbreviations: A&E accident and emergency, EIAED enzyme-inducing antiepileptic drug, GP general practitioner, nEAAED non-enzyme–active antiepileptic drug, P10–P90 10th to 90th percentile, SD standard deviation. a t test