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. 2017 Mar 23;17:57. doi: 10.1186/s12883-017-0831-4

Table 3.

Relapse characteristics according to discontinuation status at 1, 2 and 3 years

sc IFN β-1a tiw
Follow-up at 1 year Follow-up at 2 years Follow-up at 3 years
Continued Discontinued Continued Discontinued Continued Discontinued
Total patients, n (%) 2505 (63.0) 1470 (37.0) 1310 (50.5) 1282 (49.5) 736 (44.2) 928 (55.8)
Relapses per year, mean (SD) 0.18 (0.52) 0.32 (0.67) 0.14 (0.34) 0.26 (0.49) 0.12 (0.26) 0.23 (0.42)
Patients with high relapses, n (%)a 97 (3.9) 84 (5.7) 46 (3.5) 73 (5.7) 21 (2.9) 52 (5.6)

IFN, interferon, sc subcutaneous, SD standard deviation, tiw three times a week

aHigh relapse activity defined as having ≥2 relapses in the first year prior to start of subcutaneous interferon β-1a, three times weekly