Table 2.

Logistic regression analysis of adverse childhood experiences, trusted adult support in childhood, demographics and their associations with health-harming behaviours and mental well-being in adulthood

		Daily smoking 95% CIs				≤1 Portion fruit and veg/day 95% CIs				Weekly heavy drinking 95% CIs				≥2 Health- harming behaviours 95% CIs				Lower mental well-being 95% CIs
		AOR	Low	High	P	AOR	Low	High	P	AOR	Low	High	P	AOR	Low	High	P	AOR	Low	High	P
£AAA support in childhood * ACEs
Yes	0	Ref			<0.001				<0.001				<0.001				<0.001				<0.001
	1	1.26	0.98	1.63	0.068	1.26	0.93	1.69	0.133	1.69	1.22	2.35	0.002	1.54	1.07	2.19	0.019	1.32	0.96	1.81	0.083
	2–3	1.65	1.26	2.17	<0.001	1.43	1.03	1.98	0.035	1.08	0.71	1.64	0.720	1.52	1.01	2.29	0.045	1.79	1.28	2.49	<0.001
	4+	4.04	2.84	5.74	<0.001	1.09	0.63	1.89	0.754	1.70	0.97	3.00	0.066	1.72	0.94	3.13	0.078	3.27	2.16	4.96	<0.001
No	0	1.23	1.02	1.48	0.032	1.36	1.10	1.68	0.004	0.89	0.67	1.17	0.392	1.15	0.87	1.53	0.325	2.44	1.98	3.01	<0.001
	1	1.58	1.23	2.01	<0.001	1.86	1.42	2.45	<0.001	0.94	0.64	1.38	0.748	1.67	1.17	2.39	0.005	2.95	2.27	3.83	<0.001
	2–3	1.96	1.55	2.47	<0.001	1.60	1.21	2.12	0.001	1.83	1.33	2.53	<0.001	2.28	1.63	3.17	<0.001	3.69	2.86	4.76	<0.001
	4+	5.16	4.14	6.44	<0.001	3.21	2.49	4.14	<0.001	2.72	2.01	3.69	<0.001	6.16	4.61	8.24	<0.001	8.32	6.53	10.61	<0.001
UK region	Luton Wales				0.109				<0.001				<0.001				<0.001				0.035
		0.80	0.65	0.98	0.030	1.86	1.47	2.35	<0.001	1.80	1.30	2.50	<0.001	1.50	1.13	1.99	0.005	1.28	1.03	1.59	0.026
	Hertfordshire	0.88	0.72	1.09	0.241	0.98	0.77	1.26	0.877	1.23	0.87	1.74	0.237	0.94	0.70	1.28	0.712	1.01	0.81	1.26	0.920
	Northamptonshire	0.80	0.64	0.99	0.040	0.89	0.68	1.17	0.412	0.91	0.62	1.31	0.602	0.62	0.44	0.87	0.005	1.07	0.84	1.35	0.600
Deprivation quintile	Affluent 1				<0.001				<0.001				0.093				<0.001				<0.001
	2	1.39	1.14	1.70	0.001	1.28	1.01	1.61	0.041	0.79	0.60	1.05	0.110	1.30	0.96	1.75	0.086	1.42	1.15	1.76	0.001
	3	1.66	1.37	2.02	<0.001	1.57	1.26	1.97	<0.001	1.05	0.80	1.37	0.732	1.96	1.48	2.58	<0.001	1.64	1.33	2.03	<0.001
	4	1.67	1.37	2.04	<0.001	1.60	1.27	2.01	<0.001	1.21	0.92	1.59	0.175	1.83	1.37	2.44	<0.001	1.67	1.35	2.07	<0.001
	Deprived 5	3.06	2.46	3.81	<0.001	1.52	1.17	1.96	0.002	1.12	0.82	1.53	0.490	2.45	1.80	3.33	<0.001	1.98	1.56	2.52	<0.001
Age	18–29				<0.001				<0.001				<0.001				<0.001				0.789
category	30–39	0.82	0.68	0.98	0.030	0.50	0.40	0.62	<0.001	0.65	0.50	0.86	0.002	0.49	0.38	0.63	<0.001	1.08	0.88	1.32	0.465
(years)	40–49	0.66	0.55	0.80	<0.001	0.64	0.52	0.79	<0.001	0.68	0.53	0.88	0.004	0.46	0.36	0.60	<0.001	0.97	0.79	1.19	0.748
	50–59	0.84	0.69	1.01	0.065	0.61	0.49	0.76	<0.001	0.70	0.53	0.91	0.007	0.53	0.40	0.68	<0.001	1.09	0.88	1.35	0.437
	60–69	0.34	0.28	0.43	<0.001	0.50	0.40	0.62	<0.001	0.29	0.21	0.40	<0.001	0.24	0.18	0.33	<0.001	1.01	0.82	1.25	0.912
Sex$	Male	1.79	1.58	2.04	<0.001	1.96	1.69	2.28	<0.001	3.39	2.78	4.13	<0.001	2.79	2.31	3.37	<0.001	1.01	0.88	1.15	0.923
Ethnicity$	Other	0.29	0.23	0.37	<0.001	0.88	0.70	1.12	0.307	0.16	0.10	0.27	<0.001	0.35	0.25	0.50	<0.001	0.77	0.62	0.96	0.019

AAA Always Available Adult support from someone trusted in childhood, ACE Adverse Childhood Experiences, 95%CIs 95% Confidence Intervals, AOR Adjusted Odds Ratio, Ref Reference category and P values appearing in reference rows relate to testing of the overall contribution of each variable to the model. ^£Combined interaction variable between trusted adult support in childhood and ACEs. ^$For binary variables reference categories are female (for sex) and white (for ethnicity). Interactions between sex and the AAA support in childhood*ACEs variable were included in all models but did not reach significance in any of the models (daily smoking, P = 0.199; ≤1 portion of fruit and veg/day, P = 0.107; weekly heavy drinking, P = 0.472; ≥2 Health-harming behaviours, P = 0.211; lower mental well-being, P = 0.746)