Table 10.
Up- and down-regulated known genes in whole uterus of RB cows as compared with non-RB cows
| GenBank accession ID | Gene symbol | Gene description | Fold change | P-value |
|---|---|---|---|---|
| Up-regulated genes | ||||
| NM_174690 | PRSS2 | Protease, serine, 2 (trypsin 2) | 12.3 | 0.0018 |
| NM_001077112 | GSTA3 | Glutathione S-transferase, alpha 3 | 6.7 | 0.0002 |
| NM_001014878 | PIPOX | Pipecolic acid oxidase | 6.4 | <0.0001 |
| NM_174278 | CNGA1 | Cyclic nucleotide gated channel alpha 1 | 4.3 | 0.0024 |
| S82409 | IGG1C | IgG1 heavy chain constant region | 3.7 | 0.0081 |
| BC112657 | Vl1a | Immunoglobulin lambda light chain variable region | 3.7 | 0.0076 |
| S82407 | IgCgamma | IgG2a heavy chain constant region | 3.4 | 0.0347 |
| NM_001025346 | DAPL1 | death associated protein-like 1 | 3.4 | 0.0075 |
| NM_001080353 | PI3 | Peptidase inhibitor 3, skin-derived (SKALP) | 3.2 | 0.0022 |
| NM_001166616 | C5 | Complement component 5 | 2.8 | 0.0044 |
| NM_001024569 | ELF5 | E74-like factor 5 (ets domain transcription factor) | 2.8 | 0.0047 |
| NM_001075910 | CCDC113 | Coiled-coil domain containing 113 | 2.7 | 0.0432 |
| NM_173945 | NTS | Neurotensin | 2.6 | <0.0001 |
| NM_001034351 | TNNC1 | Troponin C type 1 (slow) | 2.5 | 0.0004 |
| NM_001206196 | KLHL24 | Kelch-like 24 (Drosophila) | 2.5 | <0.0001 |
| NM_001046400 | ZNRD1 | zinc ribbon domain containing 1 | 2.3 | <0.0001 |
| NM_001193109 | SDCCAG8 | Serologically defined colon cancer antigen 8 | 2.2 | 0.0001 |
| NM_174010 | CD36 | CD36 molecule (thrombospondin receptor) | 2.2 | 0.0073 |
| XM_588022 | SPOPL | Speckle-type POZ protein-like | 2.2 | <0.0001 |
| NM_173880 | H4 | Histone H4 | 2.1 | 0.0033 |
| NM_001098155 | ZNF322A | Zinc finger protein 322A | 2.1 | 0.0005 |
| NM_001035380 | GC | Group-specific component (vitamin D binding protein) | 2.0 | 0.0269 |
| NM_001035473 | GK5 | Glycerol kinase 5 | 2.0 | 0.0003 |
| Down-regulated genes | ||||
| NM_181005 | CHGA | Chromogranin A (parathyroid secretory protein 1) | 3.9 | 0.0005 |
| NM_001076073 | KRT35 | Keratin 35 | 3.3 | 0.0011 |
| NM_001034728 | THBS4 | Thrombospondin 4 | 3.2 | <0.0001 |
| NM_001206057 | CPXM2 | Carboxypeptidase X (M14 family), member 2 | 3.1 | <0.0001 |
| NM_001143735 | PRF1 | Perforin 1 (pore forming protein) | 3.0 | 0.0090 |
| NM_001002763 | CDH1 | Cadherin 1, type 1, E-cadherin (epithelial) | 2.9 | 0.0097 |
| NM_176851 | FUT5 | Fucosyltransferase 5 (alpha (1,3) fucosyltransferase) | 2.7 | 0.0038 |
| XM_002685338 | IFIH1 | Interferon induced with helicase C domain 1 | 2.5 | 0.0040 |
| NM_001081734 | MOCS3 | Molybdenum cofactor synthesis 3 | 2.5 | 0.0465 |
| NM_174039 | DPP4 | Dipeptidyl-peptidase 4 | 2.4 | 0.0158 |
| NM_001102080 | CSNK1D | Casein kinase 1, delta | 2.3 | 0.0144 |
| NM_001102060 | TBC1D10C | TBC1 domain family, member 10C | 2.3 | 0.0391 |
| NM_001081539 | C11H2orf49 | Chromosome 11 open reading frame, human C2orf49 | 2.3 | 0.0354 |
| AF068848 | VpreB | Surrogate light chain | 2.3 | 0.0204 |
| NM_001127317 | MIC1 | Major histocompatibility class I related protein | 2.2 | 0.0135 |
| NM_205801 | CLDN3 | Claudin 3 | 2.2 | 0.0196 |
| NM_001077887 | CLASRP | CLK4-associating serine/arginine rich protein | 2.2 | 0.0245 |
| NM_174513 | ADAP1 | ArfGAP with dual PH domains 1 | 2.1 | 0.0169 |
| NM_001105478 | SSLP1 | Secreted seminal-vesicle Ly-6 protein 1 | 2.1 | 0.0004 |
| NM_001077962 | STAC | SH3 and cysteine rich domain | 2.1 | <0.0001 |
| XM_002687754 | PLEKHA5 | Pleckstrin homology domain containing, family A member 5 | 2.1 | 0.0003 |
| NM_001101239 | GRP | Gastrin-releasing peptide | 2.1 | 0.0059 |
| NM_001205648 | SLC39A2 | Solute carrier family 39 (zinc transporter), member 2 | 2.0 | 0.0001 |