Table 1.

Seven pro-angiogenic pathways are included in this study

Pathways	ID	Number of genes	Gene symbol
MAPK	(1)	6	ETS1 JUN MAPK1 MAPK8 MAPK14 MAP4K4
PI3K-AKT	(2)	8	AKT1 FOXO1 FOXO3 PIK3CA PIK3CB PIK3CD PIK3CG PTEN
NOTCH	(3)	10	DLL1 DLL3 DLL4 JAG1 JAG2 NOTCH1 NOTCH2 NOTCH3 NOTCH4 RBPJ
NF-κB	(4)	5	NFKB1 NFKB2 REL RELA RELB
JAK-STAT	(5)	4	CISH JAK2 STAT1 STAT3
HIF-VEGF	(6)	14	ARNT EGLN1 EPAS1 FIGF FLT1 FLT4 HIF1A KDR NRP1 NRP2 PGF VEGFA VEGFB VEGFC
ANG-TIE	(7)	6	ANGPT1 ANGPT2 ANGPTL3 ANGPTL4 TEK TIE1