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. 2016 Dec 15;15(2):635–642. doi: 10.3892/mmr.2016.6050

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Histological changes of rat lung tissues stained with hematoxylin and eosin (A) Control group (Control); (B) sham operation group (Sham); (C) CLP operation group (CLP); (D) DXM group (DXM); (E) APZ antagonizing group (APZ). Magnification, ×4. (F) The histological changes of lung tissue presented in A-E were magnified (magnification, ×40) and scored and the data were presented as the mean ± standard error. The CLP and APZ groups demonstrated mild to moderate injury, whilst Sham and DXM groups demonstrated minimal to mild injury. #P<0.01, vs. Control and CLP group. *P<0.001, vs. CLP and APZ group. CLP, cecal ligation and puncture; DXM, dexmedetomidine; APZ, atepamezole.