Table II.
Comparison of liver function in the NC, YGD and HGF groups.
| Group | n | ALT (IU/l) | AST (IU/l) | Alb (g/l) | TBil (umol/l) | DBil (umol/l) | CHE (U/l) | ALP (IU/l) | GGT (IU/l) |
|---|---|---|---|---|---|---|---|---|---|
| NC week 1 | 10 | 143.00±2.16 | 460.25±6.40 | 21.38±0.25a | 3.55±0.26 | 2.25±0.13 | 35.35±1.08 | 183.50±2.08 | 1.38±0.07 |
| NC week 2 | 10 | 142.20±1.92 | 406.80±10.96b | 22.00±0.29a,b | 3.36±0.23 | 1.78±0.28& | 40.00±2.45b | 184.40±3.58 | 1.29±0.10b |
| NC week 3 | 10 | 141.20±10.96 | 378.60±2.07a,c | 27.04±0.48a,c | 3.42±0.19 | 1.38±0.19c | 39.32±0.47 | 174.80±67.94 | 1.29±0.06 |
| NC week 4 | 14 | 137.80±3.56 | 360.40±9.81a,d | 29.08±0.37a,d | 3.42±0.26 | 1.48±0.24 | 40.46±1.55 | 175.60±17.95 | 1.08±0.06a,d |
| HGF week 1 | 10 | 80.33±28.71a,k | 196.50±3.62a,k | 29.33±4.46a,k | 3.53±0.22 | 1.65±0.19k | 42.03±0.57k | 159.17±23.34a | 1.47±0.02k |
| HGF week 2 | 10 | 57.00±4.69a,1 | 148.60±2.07a,e,l | 29.64±0.94a,l | 3.50±0.16 | 1.00±1.47 | 45.40±10.88 | 147.20±96.83 | 1.22±0.03e,l |
| HGF week 3 | 10 | 40.80±3.27a,f,m | 138.20±2.59a,f,m | 33.76±0.80a,f,m | 3.14±0.23a,f | 0.72±0.19 | 60.26±0.58a,f,m | 130.00±27.51a | 1.20±0.03m |
| HGF week 4 | 14 | 39.60±7.02a,n | 116.80±4.66a,g,n | 35.58±0.97a,g,n | 3.00±0.16a,n | 0.08±0.64a,n | 67.00±7.07a,n | 69.32±1.19a,g,n | 1.19±0.02n |
| YGD week 1 | 10 | 70.60±20.91a,k | 184.60±93.06a,k | 25.78±0.51a,k | 3.60±0.16 | 1.40±0.43k | 46.60±0.92a,k,o | 163.52±2.92a,k | 1.47±0.18 |
| YGD week 2 | 10 | 51.02±13.35a,l | 163.40±4.51a,l,p | 32.04±4.15a,h,l | 3.50±0.29 | 1.30±0.16a | 51.00±4.30a,l | 148.80±3.35a,h,l | 1.46±0.02l,p |
| YGD week 3 | 10 | 49.80±1.92a,m,q | 122.00±2.55a,i,m,q | 33.30±1.40a,m | 3.10±0.50 | 0.82±0.19a,i,m | 56.20±1.48a,i,m,q | 128.40±54.29 | 1.30±0.05i,q |
| YGD week 4 | 14 | 35.00±3.16a,j,n | 107.20±4.66a,j,n,r | 36.36±2.00a,j,n | 3.04±0.38a | 0.5±0.16a,j,n | 73.96±2.42a,j,n | 120.00±2.92a,n,r | 1.06±0.10a,j,r |
Data are presented as the mean ± standard deviation.
a
P<0.05 vs. model week 4
b
P<0.05 vs. NC week 1
c
P<0.05 vs. NC week 2
d
P<0.05 vs. NC week 3
e
P<0.05 vs. HGF week 1
f
P<0.05 vs. HGF week 2
g
P<0.05 vs. HGF week 3
h
P<0.05 vs. YGD week 1
i
P<0.05 vs. YGD week 2
j
P<0.05 vs. YGD week 3
k
P<0.05 vs. NC week 1
l
P<0.05 vs. NC week 2
m
P<0.05 vs. NC week 3
n
P<0.05 vs. NC week 4
o
vs. HGF week 1
p
vs.HGF week 2
q
vs. HGF week 3
r
vs. HGF week 4. ALT, alanine aminotransferase; AST, aspartate aminotransferase; Alb, albumin; TBil, total bilirubin; DBil, direct bilirubin; CHE, cholinesterase; ALP, alkaline phosphatase; GGT, gamma-glutamyltranspeptidase; HGF, hepatocyte growth factor; YGD, Yi GuanJian decoction; NC, negative control.