Table III.
Group | n | a-SMA | CXCR4 | ERK1 | ERK2 | NF-κB p65 | β-catenin |
---|---|---|---|---|---|---|---|
Control | 20 | 0.945±0.013 | 0.277±0.019 | 0.115±0.011 | 0.313±0.014 | 0.728±0.003 | 0.567±0.008 |
Model week 4 | 10 | 7.351±0.051a | 0.312±0.014 | 0.373±0.011a | 0.579±0.002a | 4.211±0.021a | 2.376±0.024a |
YGD week 1 | 10 | 4.309±0.006a,b | 0.356±0.008a,b | 0.482±0.020a,b | 0.687±0.025a,b | 2.803±0.005a,b | 1.842±0.006a,b |
YGD week 2 | 10 | 3.188±0.017a,b,c | 0.523±0.002a,b,c | 0.610±0.017a,b,c | 1.413±0.025a,b,c | 1.765±0.005a,b,c | 1.189±0.013a,b,c |
YGD week 3 | 10 | 2.647±0.010a,b,d | 0.829±0.004a,b,d | 0.685±0.032a,b,d | 1.617±0.020a,b,d | 0.801±0.007a,b,d | 0.784±0.008a,b,d |
YGD week 4 | 14 | 1.103±0.022a,b,e | 1.205±0.010a,b,e | 1.125±0.080a,b,e | 2.992±0.141a,b,e | 0.742±0.002a,b,e | 0.569±0.001b,e |
Data are presented as the mean ± standard deviation.
P<0.05 vs. control
P<0.05 vs. model week 4
P<0.05 vs. YGD week 1
P<0.05 vs. YGD week 2
P<0.05 vs. YGD week 3. YGD, Yi GuanJian decoction; α-SMA, α-smooth muscle actin; CXCR4, C-X-C chemokine receptor type 4; ERK1/2, extracellular signal-regulated kinase 1/2; NF-κB p65, nuclear factor κB p65 subunit.