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Resveratrol upregulates the protein expression of SIRT1. The results of the western blot analysis showed that the protein expression levels of SIRT1 were elevated in the 20 and 80 µmol/l resveratrol treatment groups, compared with control (*P<0.05). Protein expression of SIRT1 was downregulated in the 20 µmol/l+siRNA group (*P<0.05, vs. 20 µmol/l group) and the 80 µmol/l+siRNA group (*P<0.05, vs. 80 µmol/l group). Res, resveratrol; siRNA, small interfering RNA; SIRT1, sirtuin 1.
