Table I.
Gene transcripts.
| A, Top 20 gene transcripts with the highest magnitude fold-change in gene expression upregulation in nodular basal cell carcinomas vs. hair shafts, sorted by the false discovery rate (q-value) | ||||
|---|---|---|---|---|
| Gene product description | Gene name | GenBank accession number | Fold-change | q-value (%) |
| Dipeptidylpeptidase IV (CD26, adenosine | DPP4 | NM_001935 | 11.13121 | 0 |
| Rag D protein deaminase complexing protein 2) | RAGD | AL137502 | 8.835887 | 0 |
| DKFZP564O0463 protein | DKFZP564O0463 | AK001693 | 2.87002 | 0 |
| Propionyl coenzyme A carboxylase, β polypeptide | PCCB | NM_000532 | 37.27286 | 0.326689 |
| DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome | DBY | NM_004660 | 18.25926 | 0.326689 |
| Ras homolog gene family, member A | ARHA | NM_001664 | 7.591441 | 0.326689 |
| Ubiquitin-like 3 | UBL3 | NM_007106 | 7.215993 | 0.326689 |
| Baculoviral IAP repeat-containing 3 | BIRC3 | AF070674 | 7.08567 | 0.326689 |
| Small nuclear ribonucleoprotein polypeptide E | SNRPE | NM_003094 | 5.495296 | 0.326689 |
| Splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | SFRS10 | NM_004593 | 5.367942 | 0.326689 |
| Proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | PSMD5 | BC014478 | 4.612349 | 0.326689 |
| Ubiquitously transcribed tetratricopeptide repeat gene, X chromosome | UTX | NM_021140 | 4.392788 | 0.326689 |
| Methionyl aminopeptidase 2 | METAP2 | NM_006838 | 4.388392 | 0.326689 |
| Actin related protein 2/3 complex, subunit 5 (16 kDa) | ARPC5 | NM_005717 | 3.719303 | 0.326689 |
| Sin3-associated polypeptide, 18 kDa | SAP18 | NM_005870 | 2.477771 | 0.326689 |
| F-box and leucine-rich repeat protein 3A | FBXL3A | NM_012158 | 6.425926 | 0.523782 |
| β-2-microglobulin | B2M | AK026463 | 5.708535 | 0.523782 |
| A disintegrin and metalloproteinase domain 9 (meltrin γ) | ADAM9 | NM_003816 | 4.995793 | 0.523782 |
| Lactate dehydrogenase A | LDHA | NM_005566 | 4.698842 | 0.523782 |
| Protein kinase C, ζ | PRKCZ | NM_002744 | 4.646151 | 0.523782 |
| B, Top 20 gene transcripts with the highest magnitude fold-change in gene expression downregulation in nodular basal cell carcinomas vs. hair shaft, sorted by the false discovery rate (q-value) | ||||
| Gene product description | Gene name | GenBank accession number | Fold-change | q-value (%) |
| Keratin-associated protein 4.14 | KAP4.14 | NM_033059 | 0.014887 | 0 |
| Keratin-associated protein 4.10 | KAP4.10 | NM_033060 | 0.018098 | 0 |
| Keratin-associated protein 3.2 | KRTAP3.2 | NM_031959 | 0.026814 | 0 |
| Keratin-associated protein 4.8 | KRTAP4.8 | AJ406940 | 0.055245 | 0 |
| Chromosome 20 open reading frame 28 | C20orf28 | NM_015417 | 0.061437 | 0 |
| Lymphotoxin α (TNF superfamily, member 1) | LTA | NM_000595 | 0.079272 | 0 |
| Desmoplakin (DPI, DPII) | DSP | NM_004415 | 0.087855 | 0 |
| Suppressor of Ty 5 homolog (S. cerevisiae) | SUPT5H | NM_003169 | 0.089178 | 0 |
| Neuronal protein 17.3 | P17.3 | NM_019056 | 0.095102 | 0 |
| Leucine zipper protein 1 | LUZP1 | BC002428 | 0.097131 | 0 |
| Breast carcinoma amplified sequence 1 | BCAS1 | NM_003657 | 0.097779 | 0 |
| Ubiquitin fusion degradation 1-like | UFD1L | NM_005659 | 0.098738 | 0 |
| D component of complement (adipsin) | DF | NM_001928 | 0.11378 | 0 |
| Ribosomal protein S8 | RPS8 | AK023362 | 0.138395 | 0 |
| LIM and cysteine-rich domains 1 | LMCD1 | NM_014583 | 0.149755 | 0 |
| Glutamate receptor, metabotropic 2 | GRM2 | NM_000839 | 0.153922 | 0 |
| Ephrin-B2 | EFNB2 | NM_004093 | 0.157336 | 0 |
| Ribosomal protein L38 | RPL38 | NM_000999 | 0.157418 | 0 |
| Loss of heterozygosity, 12, chromosomal region 1 | LOH12CR1 | NM_058169 | 0.169164 | 0 |