Table III.
Most commonly identified categories with differences in GO categorization analysis between nodular basal cell carcinomas and hair shafts at GO level 3.
| GO category | Number of genes in category | Percentage of total genes in gene set | P-value | Benjamini |
|---|---|---|---|---|
| Regulation of cellular process | 966 | 24.8 | 3.50E-13 | 2.90E-10 |
| Negative regulation of cellular process | 297 | 7.6 | 5.20E-12 | 1.50E-09 |
| Negative regulation of biological process | 308 | 7.9 | 4.30E-12 | 1.80E-09 |
| System development | 417 | 10.7 | 1.00E-09 | 2.10E-07 |
| Regulation of programmed cell death | 147 | 3.8 | 3.30E-07 | 5.60E-05 |
| Positive regulation of cellular process | 243 | 6.2 | 5.20E-07 | 6.30E-05 |
| Positive regulation of biological process | 266 | 6.8 | 5.00E-07 | 7.00E-05 |
| Biopolymer metabolic process | 1090 | 27.9 | 8.30E-07 | 7.80E-05 |
| Organ development | 301 | 7.7 | 8.00E-07 | 8.40E-05 |
| Anatomical structure morphogenesis | 269 | 6.9 | 1.30E-06 | 1.10E-04 |
| Cell death | 206 | 5.3 | 1.70E-06 | 1.30E-04 |
| Cell cycle process | 187 | 4.8 | 2.70E-06 | 1.90E-04 |
| Organ morphogenesis | 114 | 2.9 | 3.40E-06 | 2.20E-04 |
| Regulation of metabolic process | 628 | 16.1 | 6.60E-06 | 4.00E-04 |
| Regulation of cell cycle | 137 | 3.5 | 9.80E-06 | 5.50E-04 |
| Regulation of cellular metabolic process | 604 | 15.5 | 2.00E-05 | 1.00E-03 |
| Regulation of gene expression | 582 | 14.9 | 2.10E-05 | 1.00E-03 |
| Cell differentiation | 399 | 10.2 | 4.20E-05 | 2.00E-03 |
| Regulation of protein metabolic process | 85 | 2.2 | 4.90E-05 | 2.20E-03 |
| Regulation of cell proliferation | 126 | 3.2 | 7.80E-05 | 3.30E-03 |
Top twenty categories identified are shown. GO, gene ontology.