Table II.
Lymphatic invasion and clinicopathological features of lung squamous cell carcinoma.
| Variable | No. of patients (%) | ly0-1 (%) | ly2-3 (%) | P-value |
|---|---|---|---|---|
| Age at surgery (years) | 0.910 | |||
| <68 | 53 (51.5) | 43 (81.1) | 10 (18.9) | |
| ≥68 | 50 (48.5) | 41 (82.0) | 9 (18.0) | |
| Gender | 0.230 | |||
| Male | 97 (94.2) | 78 (80.4) | 19 (19.6) | |
| Female | 6 (5.8) | 6 (100.0) | 0 (0.0) | |
| Tumor size (mm) | 0.028 | |||
| ≤30 | 39 (37.9) | 36 (92.3) | 3 (7.7) | |
| >30 | 64 (62.1) | 48 (75.0) | 16 (25.0) | |
| Lymph node metastasis | <0.001 | |||
| n(−) | 70 (68.0) | 66 (94.3) | 4 (5.7) | |
| n(+) | 33 (32.0) | 18 (54.5) | 15 (45.5) | |
| Venous invasion | 0.001 | |||
| v(−) | 53 (51.5) | 50 (94.3) | 3 (5.7) | |
| v(+) | 50 (48.5) | 34 (68.0) | 16 (32.0) | |
| Histological differentiation | 0.047 | |||
| Well, moderate | 90 (87.4) | 76 (84.4) | 14 (15.6) | |
| Poorly | 13 (12.6) | 8 (61.5) | 5 (38.5) | |
| Stromal type | 0.298 | |||
| Medullary, intermediate | 70 (68.0) | 59 (84.3) | 11 (15.7) | |
| Scirrhous | 33 (32.0) | 25 (75.8) | 8 (24.2) | |
| Infiltrating pattern | 0.142 | |||
| INFc(−) | 64 (62.1) | 55 (85.9) | 9 (14.1) | |
| INFc(+) | 39 (37.9) | 29 (74.4) | 10 (25.6) |
n(−)/n(+), lymph node metastasis negative/positive; v(−)/v(+), venous invasion negative/positive; INFc(−)/INFc(+), infiltrating component negative/positive.