Table 2. Final Full-Stay EHR Model Predicting 30-Day Readmissions (Derivation Cohort, N = 16,492).
| Odds Ratio (95% CI) | ||
|---|---|---|
|
| ||
| Univariate | Multivariate* | |
| Demographic characteristics | ||
| Age, per 10 years | 1.08 (1.05–1.11) | 1.07 (1.04–1.10) |
| Medicaid | 1.97 (1.70–2.29) | 1.55 (1.31–1.83) |
| Widow | 1.44 (1.28–1.63) | 1.27 (1.11–1.45) |
| Utilization history | ||
| Prior ED visit, per visit | 1.08 (1.06–1.10) | 1.04 (1.02–1.06) |
| Prior hospitalization, per hospitalization | 1.30 (1.27–1.34) | 1.16 (1.12–1.20) |
| Hospital and clinical factors from first day of hospitalization | ||
| Nonelective admission | 1.75 (1.51–2.03) | 1.42 (1.22–1.65) |
| Charlson Comorbidity Index, per point | 1.19 (1.17–1.21) | 1.06 (1.04–1.09) |
| Laboratory abnormalities within 24 hours of admission | ||
| Albumin <2 g/dL | 2.57 (1.82–3.62) | 1.52 (1.05–2.21) |
| Albumin 2–3 g/dL | 1.68 (1.50–1.88) | 1.20 (1.06–1.36) |
| Aspartate aminotransferase >40 U/L | 1.37 (1.22–1.55) | 1.21 (1.06–1.38) |
| Creatine phosphokinase <60 μg/L | 1.48 (1.30–1.69) | 1.28 (1.11–1.46) |
| Mean corpuscular volume >100 fL/red cell | 1.68 (1.38–2.04) | 1.32 (1.07–1.62) |
| Platelets <90 × 103/μL | 2.20 (1.77–2.72) | 1.56 (1.23–1.97) |
| Platelets >350 × 103/μL | 1.34 (1.17–1.54) | 1.24 (1.08–1.44) |
| Prothrombin time >35 seconds | 2.58 (1.74–3.82) | 1.92 (1.27–2.90) |
| Hospital and clinical factors from remainder of hospital stay | ||
| Length of stay, per day | 1.08 (1.07–1.09) | 1.06 (1.04–1.07) |
| Hospital complications | ||
| Clostridium difficile infection | 3.61 (2.19–5.95) | 2.03 (1.18–3.48) |
| Pressure ulcer | 2.43 (1.73–3.41) | 1.64 (1.15–2.34) |
| Venous thromboembolism | 2.01 (1.36–2.96) | 1.55 (1.03–2.32) |
| Laboratory abnormalities at discharge | ||
| Blood urea nitrogen >20 mg/dL | 1.86 (1.70–2.04) | 1.37 (1.24–1.52) |
| Sodium <135 mEq/L | 1.70 (1.52–1.91) | 1.34 (1.18–1.51) |
| Hematocrit <27 | 1.61 (1.40–1.85) | 1.22 (1.05–1.41) |
| Vital sign instability at discharge, per instability | 1.29 (1.20–1.40) | 1.25 (1.15–1.36) |
| Discharged to hospice | 0.51 (0.30–0.89) | 0.23 (0.13–0.40) |
NOTE: Abbreviations: CI, confidence interval; ED, emergency department.
*
Values shown reflect adjusted odds ratios and 95% CI for each factor after adjustment for all other factors listed in the table.