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. 2015 May 14;2:74–81. doi: 10.1016/j.bonr.2015.05.003

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© 2015 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Percent of bone volume with respect to total bone volume (BV/TV), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), and number of trabeculae (Tb.N) in five-month-old male Wistar rats treated with cyclosporine (CsA, 2 mg/kg/day), FK-506 (0.1 mg/kg/da), and rapamycin (RAPA, 0.05 mg/kg/day) over three months. Statistical significance: Mann–Whitney test; a: significant vs, control; BV/TV: control vs FK-506: p < 0.05 (2). Tb.Sp: control vs FK-506: p < 0.01. Tb.N: control vs FK-506: p < 0.01.