Table 1.
Baseline characteristics for the 214 study subjects who completed the study.a
| Characteristics | Placebo |
Vitamin D (10 μg) |
Vitamin D (25 μg) |
|---|---|---|---|
| N = 71 | N = 69 | N = 74 | |
| Age (years) | 39 (7.4) | 37 (7.4) | 37 (8.2) |
| Sex, n (%) | |||
| Male | 15 (21%) | 18 (26%) | 23 (31%) |
| Female | 56 (79%) | 51 (74%) | 51 (69%) |
| BMI (kg/m2) | 29.1 (5.2) | 27.2 (4.9) | 26.6 (5.1) |
| Ethnic origin (n, %) | |||
| South Asia | 27 (38%) | 25 (36%) | 29 (39%) |
| Middle East & North Africa | 12 (17%) | 7 (10%) | 12 (16%) |
| Sub-Sahara Africa | 32 (45%) | 37 (54%) | 33 (45%) |
| Time lived in Norway (years) | 13.6 (2–33) | 13.2 (1–35) | 13.3 (1–29) |
| Level of education (n, %) | |||
| ≤ 10 years | 30 (42%) | 29 (42%) | 29 (39%) |
| 11–13 years | 26 (37%) | 26 (38%) | 26 (35%) |
| ≥ 14 years | 15 (21%) | 14 (20%) | 19 (26%) |
| Serum creatinine (μmol/L)b | 56.1 (11.6) | 56.4 (14.6) | 56.6 (12.5) |
| Serum alanine transaminase (u/L) c | 22.3 (12.3) | 22.9 (11.9) | 21.7 (12.1) |
| Serum aspartate aminotransferase (u/L)d | 20.1 (6.6) | 21.0 (6.6) | 19.9 (6.7) |
| Total S-25(OH)D (nmol/L) | 29.2 (15.6) | 30.7 (20.1) | 26.8 (17.1) |
| Serum 25(OH)D3 (nmol/L) | 26.9 (15.1) | 27.2 (15.1) | 26.8 (17.1) |
| Serum 25(OH)D2 (nmol/L) | 2.3 (8.6) | 3.5 (13.5) | 0 |
| Serum calcium (mmol/L)e | 2.36 (0.10) | 2.37 (0.08) | 2.37 (0.09) |
| Serum corrected calcium (mmol/L) | 2.30 (0.08) | 2.31 (0.06) | 2.32 (0.08) |
| Serum phosphate (mmol/L)e | 1.15 (0.15) | 1.16 (0.16) | 1.13 (0.13) |
| Plasma PTH (pmol/L)f | 8.1 (4.0) | 7.1 (3.5) | 7.6 (3.8) |
| Serum P1NP (μg/L) | 44.8 (16.0) | 47.1 (17.4) | 49.0 (26.0) |
| Serum CTX-1(μg/L) | 0.19 (0.10) | 0.20 (0.10) | 0.19 (0.13) |
The mean of s-25(OH)D was 31.3 and 44 nmol/L for males and females respectively.
a
Data are mean (standard deviation) unless specified otherwise.
b
None were above the reference range (males 60–105, females 45–90 μmol/L).
c
3 males and 2 females have above the reference limit (men < 70, women < 45 U/L).
d
1 male and 1 female have above the reference limit (men < 45, women < 35 U/L).
e
Reference range for s-calcium (2.15–2.51 mmol/L) and for s-phosphate (women > 18 years: 0.85–1.50 mmol/L and men 18–49 years: 0.75–1.65 mmol/L).
f
N = 69 for placebo, 66 for 10 and 74 for 25 μg group due to 5 missing data.