Table 1.
Baseline subject characteristics.
| Disease | Number | Female | Median Age [25%–75%] | Median Observation Period [25%–75%] | Median FRAXa [25%–75%] | Bisphosphonates prescription (%) | Prior high-dose GC (%) | Fragility Fracture (%) |
|---|---|---|---|---|---|---|---|---|
| SLE | 76 | 66 (86.8) | 30.5 [24–37] | 2226 [1124–3085] | 5.3 [3.7–10.9] | 28 (36.8) | 30 (39.5) | 6 (7.8) |
| Vasculitisb | 58 | 45 (75.9) | 66 [47.8–70.8] | 1166 [618.3–2087] | 14 [6.8–24] | 38(65.5) | 9 (15.5) | 18 (31) |
| PM/DM | 51 | 34 (66.7) | 58 [47–69] | 1655 [676–2587] | 9 [5.9–14] | 34 (66.7) | 5 (9.8) | 18 (35.3) |
| AOSD | 12 | 7 (58.3) | 37.5 [26–56] | 1613 [1215–2335] | 7.2 [3.2–9.8] | 7 (58.3) | 1 (8.3) | 2 (16.7) |
| MCTD | 7 | 6 (75) | 42 [35–54] | 1975 [1768–2540] | 5.7 [2.8–10] | 6 (85.7) | 2 (29) | 1 (14.2) |
| Othersc | 25 | 12 (48) | 63 [57.5–70] | 833 [283–2650] | 6.7 [4.9–13] | 9 (36) | 4 (16) | 12 (48) |
| Total | 229 | 170 (74.2) | 49 [31–66] | 1558 [803–2596] | 9 [5.2–15] | 122 (53.2) | 51 (22.2) | 57c (24.9) |
AOSD = adult-onset Still's disease.
FRAX is calculated for postmenopausal women and men over 40 of age.
Vasculitis syndromes: Takayasu arteritis (11); giant-cell arteritis (11); microscopic polyangiitis (10); granulomatosis with polyangiitis (7); eosinophilic granulomatosis with polyangiitis (6); Behcet's disease (5); rheumatoid vasculitis (4); unclassified vasculitis (4). bOther diseases: IgG4-related disease (4); Castleman's disease (3); overlap syndrome (3); sarcoidosis (2); diffuse fasciitis (3); systemic sclerosis (2); relapsing polychondritis (2); idiopathic thrombocytopenia (1); autoimmune haemolytic anaemia (1); autoimmune hepatitis (1); eosinophilic pneumonia (1); and pachymeningitis (1).
52 clinical spinal, 3 hip, 1 humerus and 1 wrist fracture.