Table 1.
Serum biochemistries for WT, WT/Hif1α(Cre+), Hyp, and Hyp/Hif1α(Cre+) mice (#p < 0.01; *p < 0.05; compared to genotype control).
| Alk. Phos. | Phosphate | Calcium | Creatinine | Total iron | ||
|---|---|---|---|---|---|---|
| Male | WT | 91.57 ± 5.35 |
11.74 ± 0.71 |
11.79 ± 0.54 |
0.42 ± 0.04 |
209.18 ± 12.08 |
| WT-Hif1α(Cre+) | 78.00 ± 12.00 |
14.63 ± 2.46 |
11.06 ± 0.20 |
0.43 ± 0.04 |
220.73 ± 16.95 |
|
| Hyp | 416.62# ± 17.57 |
8.92* ± 0.45 |
10.50 ± 0.37 |
0.40 ± 0.03 |
240.27 ± 10.60 |
|
| Hyp-Hif1α(Cre+) | 410.50# ± 28.52 |
9.55* ± 1.19 |
10.86 ± 0.26 |
0.35 ± 0.04 |
233.24 ± 12.13 |
|
| Female | WT | 114.90 ± 3.48 |
12.13 ± 1.03 |
10.95 ± 0.30 |
0.33 ± 0.04 |
206.89 ± 8.70 |
| WT-Hif1α(Cre+) | 114.00 ± 3.96 |
11.60 ± 0.47 |
10.65 ± 0.30 |
0.41 ± 0.04 |
214.77 ± 8.70 |
|
| Hyp | 275.50# ± 13.99 |
7.65* ± 0.46 |
10.43 ± 0.19 |
0.40 ± 0.01 |
200.77 ± 12.32 |
|
| Hyp-Hif1α(Cre+) | 276.43# ± 12.17 |
8.94* ± 0.85 |
9.95 ± 0.31 |
0.32 ± 0.05 |
231.68 ± 15.33 |
|