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Germ cell development in the mouse testis. In the male embryo, the primordial germ cells (PCGs) give rise to quiescent gonocytes. At birth, the gonocytes give rise to spermatogonia stem cells (SSCs) that proliferate, enter meiosis, and differentiate into spermatids. The level of key regulatory proteins (illustrated as high or low) changes as the germ cell passes through each stage. Stra8, Stimulated by retinoic acid 8; Sycp3, Synaptonemal complex protein 3.
