Table 7.

Risk factors for septic shock

Risk factor	Univariate analysis			Multivariate analysis
	HR	95% CI	p	HR	95% CI	p
Sex (female)	3.095	1.194–8.019	0.0200	1.213	0.377–3.905	0.7464
Age	1.013	0.985–1.041	0.3753
Cancer	0.260	0.085–0.794	0.0181	0.500	0.132–1.894	0.3077
Diabetes mellitus	1.469	0.497–4.372	0.4872
Cerebral disease	1.552	0.207–11.639	0.6691
Neurological disease	0.750	0.065–8.646	0.8176
Leukocyte	1.000	1.000–1.000	0.0348	1.000	1.000–1.000	0.9962
Platelet	0.915	0.863–0.970	0.0029	0.957	0.899–1.018	0.1604
C-reactive protein	1.117	1.060–1.177	<0.0001	1.098	1.030–1.170	0.0041
Urological obstruction	0.484	0.180–1.301	0.1502
E. coli	2.046	0.775–5.402	0.1482
E. coli (ESBL)	2.821	0.622–12.785	0.1787
E. cloacae	1.552	0.207–11.639	0.6691
E. faecalis	0.489	0.049–4.928	0.5438
K. pneumoniae	0.228	0.026–1.193	0.1812
P. aeruginosa	0.280	0.031–2.521	0.2562
S. aureus	0.489	0.049–4.928	0.5438
P. mirabillis	1.553	0.092–25.468	0.7656
Ceftazidime resistance	2.067	0.509–8.402	0.3100
Imipenem resistance	0.394	0.076–2.037	0.2665
Levofloxacin resistance	0.851	0.293–2.473	0.7665

CI: confidence interval; ESBL: extended-spectrum beta lactamase; HR: hazard ratio.