FIG 1.

Peptide-conjugate (RXR)₄XB was effective at delivering PMO into P. aeruginosa. (a) Heat map comparison of MICs for PPMOs with various peptide-conjugates against P. aeruginosa strains grown in MHII with PMBN at 2 μg/ml. (b) Heat map comparison of MICs for 5′ versus 3′ (RXR)₄XB-conjugated PPMOs against P. aeruginosa strains grown in MHII with PMBN at 2 μg/ml. (c) Heat map comparison of MICs for lead sequence PPMOs against P. aeruginosa strains grown in MHII with PMBN at 2 μg/ml, MOPS, and MHII alone.