Association between K13 mutations and parasite clearance half-life in Vietnam, 2009 to 2016. The median (interquartile range) half-life for each mutation (shown as gray lines) is as follows: 1.96 h (1.63 to 2.73 h) for the wild type, 6.8 h (3.69 to 7.42 h) for Tyr493His, 6 h (4.81 to 7.04 h) for Arg539Thr, 6.7 h (5.9 to 8.02 h) for Ile543Thr, 6.4 h (4.39 to 7.08 h) for Pro553Leu, 6.8 h (6.22 to 7.59 h) for Val568Gly, and 6.9 h (6.33 to 8.14 h) for Cys580Tyr.