TABLE 2.
Parameter | Pre-PCR (n = 27) | PCR (n = 30) | Difference | P value | 95% CI |
---|---|---|---|---|---|
Duration of therapy | |||||
Hours | 74 ± 48.9 | 27.4 ± 18.7 | 46.6 | <0.0001 | 27.3–65.8 |
Days | 4.0 ± 2.0 | 2.13 ± 0.86 | 1.9 | <0.0001 | 1.06–2.67 |
Total i.v.a vancomycin doses | 4.2 ± 3.1 | 1.7 ± 1.5 | 2.44 | 0.005 | 1.12–3.77 |
Total i.v. vancomycin (mg) | 5,394.4 ± 3,483.5 | 2,865 ± 2,579.8 | 2,529.4 | 0.003 | 912.9–4,145.9 |
Vancomycin level obtained (%) | 13 (48.1) | 5 (16.7) | 31.4 | 0.02 | |
No. of vancomycin levels (%) | |||||
0 | 14 (51.9) | 25 (83.3) | |||
1 | 8 (29.6) | 5 (16.7) | |||
2 | 5 (18.5) | 0 (0) | |||
Per patient avg no. of levels | 0.67 | 0.17 | 0.50 |
i.v., intravenous.