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. 2017 Mar 24;61(4):e02410-16. doi: 10.1128/AAC.02410-16

TABLE 2.

Precision and accuracy of intrarun and interrun for samples processed with the lower limit of quantitation and low, middle, and high quality control levelsa

Sample Nominal concnb % obtained from nominal concn Precision (% CV)
Accuracy (% RSE)
Intrarun Interrun Intrarun Interrun
Plasma 0.10 105.12 2.92 3.98 5.12 1.54
0.25 106.63 3.57 4.72 6.63 9.40
50.00 92.08 6.36 4.22 −7.92 −4.90
75.00 102.03 2.00 8.70 2.03 −0.03
Spleen 0.10 116.07 12.23 8.63 16.07 6.73
0.25 95.30 7.79 7.36 −4.70 −6.08
50.00 98.08 3.12 7.13 −1.92 −0.27
75.00 101.05 2.81 6.17 1.05 0.47
Brain 0.10 112.72 8.30 12.14 12.72 15.76
0.25 90.29 10.44 7.94 −9.71 −3.02
50.0 88.01 9.35 8.37 −11.99 −8.72
75.0 99.59 4.88 4.11 −0.41 1.90
Colon 0.10 115.59 6.22 9.30 15.59 13.47
0.25 105.17 4.08 7.43 5.17 5.31
50.00 93.99 4.17 5.97 −6.01 −0.71
75.00 92.55 4.10 4.20 −7.45 −2.69
Heart 0.10 108.56 6.26 11.86 8.56 8.68
0.25 105.57 4.86 6.05 5.57 3.16
50.00 100.17 3.32 5.54 0.17 −4.08
75.00 101.95 5.33 6.07 1.95 −4.03
Liver 0.20 97.73 3.47 6.80 −2.27 −0.87
0.50 98.56 4.80 7.19 −1.44 −0.93
50.00 91.87 2.46 12.84 −8.13 −1.75
75.00 100.32 1.03 5.94 0.32 1.94
Lung 0.10 102.32 12.51 9.11 2.32 2.75
0.25 87.93 10.01 10.29 −12.07 −3.54
50.0 103.51 5.25 7.31 3.51 1.21
75.0 102.21 8.07 7.76 2.21 −0.96
Kidney 0.10 104.18 5.25 12.87 4.18 −11.89
0.25 105.42 5.34 4.10 5.42 −7.38
50.0 99.01 5.33 6.15 −0.99 −0.68
75.0 105.35 1.11 3.00 5.35 3.06
a

Precision and accuracy were determined using an analytical method. CV, coefficient of variation; RSE, relative standard error.

b

Nominal concentrations are in micrograms per milliliter (plasma) or micrograms per gram (tissue).