TABLE 2.
Sample | Nominal concnb | % obtained from nominal concn | Precision (% CV) |
Accuracy (% RSE) |
||
---|---|---|---|---|---|---|
Intrarun | Interrun | Intrarun | Interrun | |||
Plasma | 0.10 | 105.12 | 2.92 | 3.98 | 5.12 | 1.54 |
0.25 | 106.63 | 3.57 | 4.72 | 6.63 | 9.40 | |
50.00 | 92.08 | 6.36 | 4.22 | −7.92 | −4.90 | |
75.00 | 102.03 | 2.00 | 8.70 | 2.03 | −0.03 | |
Spleen | 0.10 | 116.07 | 12.23 | 8.63 | 16.07 | 6.73 |
0.25 | 95.30 | 7.79 | 7.36 | −4.70 | −6.08 | |
50.00 | 98.08 | 3.12 | 7.13 | −1.92 | −0.27 | |
75.00 | 101.05 | 2.81 | 6.17 | 1.05 | 0.47 | |
Brain | 0.10 | 112.72 | 8.30 | 12.14 | 12.72 | 15.76 |
0.25 | 90.29 | 10.44 | 7.94 | −9.71 | −3.02 | |
50.0 | 88.01 | 9.35 | 8.37 | −11.99 | −8.72 | |
75.0 | 99.59 | 4.88 | 4.11 | −0.41 | 1.90 | |
Colon | 0.10 | 115.59 | 6.22 | 9.30 | 15.59 | 13.47 |
0.25 | 105.17 | 4.08 | 7.43 | 5.17 | 5.31 | |
50.00 | 93.99 | 4.17 | 5.97 | −6.01 | −0.71 | |
75.00 | 92.55 | 4.10 | 4.20 | −7.45 | −2.69 | |
Heart | 0.10 | 108.56 | 6.26 | 11.86 | 8.56 | 8.68 |
0.25 | 105.57 | 4.86 | 6.05 | 5.57 | 3.16 | |
50.00 | 100.17 | 3.32 | 5.54 | 0.17 | −4.08 | |
75.00 | 101.95 | 5.33 | 6.07 | 1.95 | −4.03 | |
Liver | 0.20 | 97.73 | 3.47 | 6.80 | −2.27 | −0.87 |
0.50 | 98.56 | 4.80 | 7.19 | −1.44 | −0.93 | |
50.00 | 91.87 | 2.46 | 12.84 | −8.13 | −1.75 | |
75.00 | 100.32 | 1.03 | 5.94 | 0.32 | 1.94 | |
Lung | 0.10 | 102.32 | 12.51 | 9.11 | 2.32 | 2.75 |
0.25 | 87.93 | 10.01 | 10.29 | −12.07 | −3.54 | |
50.0 | 103.51 | 5.25 | 7.31 | 3.51 | 1.21 | |
75.0 | 102.21 | 8.07 | 7.76 | 2.21 | −0.96 | |
Kidney | 0.10 | 104.18 | 5.25 | 12.87 | 4.18 | −11.89 |
0.25 | 105.42 | 5.34 | 4.10 | 5.42 | −7.38 | |
50.0 | 99.01 | 5.33 | 6.15 | −0.99 | −0.68 | |
75.0 | 105.35 | 1.11 | 3.00 | 5.35 | 3.06 |
Precision and accuracy were determined using an analytical method. CV, coefficient of variation; RSE, relative standard error.
Nominal concentrations are in micrograms per milliliter (plasma) or micrograms per gram (tissue).