TABLE 3.

Short-term, on-instrument autosampler, freeze-thaw, and long-term stabilities of samples processed with low and high quality control levels^a

Sample	NCb	% obtained from NC	Short-term stability		% obtained from NC	On-instrument autosampler stability		% obtained from NC	Freeze-thaw stability		% obtained from NC	Long-term stability
			Precision (% CV)	Accuracy (% RSE)		Precision (% CV)	Accuracy (% RSE)		Precision (% CV)	Accuracy (% RSE)		Precision (% CV)	Accuracy (% RSE)
Plasma	0.25	107.39	1.91	7.39	105.95	7.70	5.95	108.59	6.51	8.59	95.00	9.07	−5.00
	75.00	92.17	7.15	−7.83	94.47	2.19	−5.53	94.96	3.54	−5.04	97.23	9.95	−2.77
Spleen	0.25	101.38	7.24	1.38	101.19	5.36	1.19	95.63	4.81	−4.37	97.40	9.85	−2.60
	75.00	100.31	12.22	0.31	98.58	2.10	−1.42	104.61	7.69	4.61	103.44	6.35	3.44
Brain	0.25	90.93	6.59	−9.07	97.35	5.04	−2.65	98.27	1.55	−1.73	93.62	4.77	−6.38
	75.0	91.42	8.36	−8.58	95.11	6.14	−4.89	98.06	3.74	−1.94	91.20	10.65	−8.80
Colon	0.25	101.08	5.48	1.08	104.78	3.44	4.78	92.91	4.72	−7.09	101.89	11.65	1.89
	75.00	93.61	4.24	−6.39	92.01	4.00	−7.99	96.49	3.38	−3.51	110.99	7.55	10.99
Heart	0.25	90.68	10.67	−9.32	112.38	1.56	12.38	88.14	5.50	−11.86	84.19	5.64	−14.40
	75.00	95.93	4.04	−4.07	89.82	2.22	−10.18	105.77	4.35	5.77	104.43	1.58	4.43
Liver	0.50	108.67	6.74	8.67	100.32	12.07	0.32	96.85	10.92	−3.15	96.29	10.57	−3.71
	75.00	102.78	5.31	2.78	95.65	11.68	−4.35	95.55	9.19	−4.45	99.79	4.08	−0.21
Lung	0.25	89.90	8.02	−10.10	101.77	11.11	1.77	94.78	7.68	−5.22	92.44	4.51	−7.56
	75.0	99.06	7.15	−0.94	92.58	10.20	−7.42	92.03	10.29	−7.97	100.69	4.57	0.69
Kidney	0.25	89.94	3.43	−10.06	88.11	6.80	−11.89	91.64	4.18	−8.36	104.15	4.96	4.15
	75.0	102.95	2.19	2.95	103.94	0.99	3.94	98.41	5.07	−1.59	107.94	13.92	7.94

^aPrecision and accuracy were determined using an analytical method. CV, coefficient of variation; RSE, relative standard error.

^bNominal concentrations (NC) are in micrograms per milliliter (plasma) or micrograms per gram (tissue).